About Us


Isoprime Ltd is an established and traditional manufacturer of Stable Isotope Ratio Mass Spectrometers (IRMS) and offers a comprehensive range of complimentary inlet systems. Our products are solely designed for high performance measurements of carbon, hydrogen, oxygen, nitrogen and sulphur isotopes in solid, liquid and gaseous samples.Based at Isoprime House in Cheadle Hulme, UK, Isoprime Ltd supplies IRMS instrumentation around the globe through its extensive sales network and ensures that users receive excellent support from its highly trained local service engineers. Isoprime ltd is committed to enhancing its products through a dedicated R&D department working alongside highly qualified application scientists to provide the latest in IRMS techniques and capabilities. Our IRMS experts also give regular training courses to customers of all experience levels in our well-equipped applications laboratory.

Isoprime Ltd is a wholly owned daughter company of Elementar Analysensysteme GmbH and is the sole distributor of Elementar products to the United Kingdom. Whether you are looking for a new elemental analyser or support for an existing Elementar instrument, Isoprime Ltd can provide the perfect solution.

The IsoPrime100 has been developed to meet the needs of the world’s best scientists and technologists, who demand the most advanced, efficient and practical solutions, for IRMS applications. We offer a comprehensive range of inlet systems suitable for the IsoPrime100 mass spectrometer. They allow a broad range of sample types to be analysed to a level of precision to suit your requirements. Naturally, both Dual Inlet (DI) and Continuous Flow (CF) needs are catered for in our product line. Our inlets are designed to carefully combine high sample throughput, high precision and day-to-day reliability. IsoPrime100 is the IRMS of choice for experts in the fields of hydrology, environmental studies, medical sciences, food authentication and geological sciences.

IsoPrime100 IRMS
The IsoPrime100 is the next generation of the world renowned IsoPrime gas source stable isotope ratio mass spectrometer. Building on a legacy of almost 40 years, the IsoPrime100 is the most compact, high performance IRMS on the market and is the latest development from IsoPrime Ltd. At the heart of the new IsoPrime100 is a completely redesigned 100V head amplifier which offers unrivalled dynamic range as well as automatic gain-switching. Enhancements to the ionisation source have resulted in higher instrument performance with exceptional sensitivity, precision and accuracy as well as a market leading low H3+ correction factor of ≤ 8.0ppm/nA.

Stable isotope data can be relevant to a range of research areas in geology, hydrology, food authentication, forensics, medicine and environmental sciences. Some example applications of IsoPrime customers include, but are not limited to:

  • δ18O and δD analysis of ice core samples
  • δ13C and δD of natural gas and oil fractions
  • multielemental (CHNS) analysis of food products for authentication purposes
  • N2O isotopomers
  • δD and δ18O of body water to calculate energy expenditure
  • δ13C and δ18O analysis of carbonates
  • Food web studies
  • δ13C analysis of honey for detecting adulteration
  • Compound specific δ13C analysis of plant waxes
  • δ13C and δ18O analysis of CO2 in air
  • δ15N analysis of nitrate and ammonium in soils and waters
  • δ13C of dissolved inorganic carbon
  • δ13C of testosterone for doping detection
  • δ18O analysis of water in wine
  • δ13C and δ18O analysis of ethanol
  • δ13C analysis of methane in air samples
  • δ15N and δ18O of N2O
  • CHNS analysis of solid samples such as soil and leaves
  • δ13C analysis of sugars, amino acids and organic acids
  • δ34S of sulphates
  • δ18O of sulphates and phosphates
  • δD and δ18O of water